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Cheilitis Glandularis

Cheilitis Glandularis
Etiology • Unknown; may be familial in some cases • Alternative etiologies include infectious, actinic, atopic, and
factitious origins
Clinical Presentation • Usually involves lower lip of adult males (may occasionally
involve both lips) • Tender eversion and enlargement of lip • Mucoid to purulent secretion at minor salivary gland orifices
Diagnosis • Microscopy shows nonspecific inflammation. • Biopsy results may show labial salivary gland hyperplasia and
ductal ectasia. • Sialadenitis


Differential Diagnosis • Granulomatous cheilitis (orofacial granulomatosis) • Atopic cheilitis • Actinic or photosensitivity cheilitis
Treatment • Surgical excision • Suppressive therapy with broad-spectrum antibiotics • Intralesional corticosteroid injections
Prognosis • Chronic • Good