Etiology • Autosomal-dominant condition • Association of multiple osteomas, colonic and rectal polyposis,
cutaneous and mesenteric fibromas, epidermoid cysts of skin • Gene is located on chromosome 5q
Clinical Presentation • Early clinical indicators may be osteomas of jaws and facial
bones. • Colorectal polyps usually develop after osteomas. • Facial asymmetry • Multiple impacted teeth and odontomas not uncommon
Radiographic Findings • Well-defined, sclerotic, opaque masses • Endosteal or periosteal origin • Impacted and supplementary teeth are usually noted. • Multiple odontomas may be noted.
Diagnosis • Family history • Multiple jaw bone, facial bone osteomas • Concomitant polyposis of colon
Differential Diagnosis • Exostoses of mandible/maxilla
Treatment • Osteoma treatment is elective/cosmetic.
• Prophylactic colectomy as all patients ultimately develop coloncutaneous and mesenteric fibromas, epidermoid cysts of skin • Gene is located on chromosome 5q
Clinical Presentation • Early clinical indicators may be osteomas of jaws and facial
bones. • Colorectal polyps usually develop after osteomas. • Facial asymmetry • Multiple impacted teeth and odontomas not uncommon
Radiographic Findings • Well-defined, sclerotic, opaque masses • Endosteal or periosteal origin • Impacted and supplementary teeth are usually noted. • Multiple odontomas may be noted.
Diagnosis • Family history • Multiple jaw bone, facial bone osteomas • Concomitant polyposis of colon
Differential Diagnosis • Exostoses of mandible/maxilla
Treatment • Osteoma treatment is elective/cosmetic.
adenocarcinomas • Genetic counseling
Prognosis • Relates to colon adenocarcinoma development and behavior