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Juvenile Ossifying Fibroma

Juvenile Ossifying Fibroma
Etiology • A rapidly evolving variant of ossifying fibroma of the young • Cause unknown
Clinical Presentation • Onset between 5 and 15 years of age • Rapid growth over several weeks • Maxilla and paranasal areas predominate • Tooth displacement common
Radiographic Findings • Well-defined radiolucency • Focal mineralization may be noted. • Adjacent bone may be eroded or destroyed.

Microscopic Findings • Prominent stromal cellularity • Woven bone and/or psammomatous calcifications • Plump osteoblast rimming
Diagnosis • Correlation of histologic and radiographic findings
Differential Diagnosis • Osteosarcoma • Central giant cell granuloma • Odontogenic tumor
Treatment • Wide local excision or resection • Reconstruction
Prognosis • Recurrence rate of 30 to 50%