• Topical therapy
Therapeutics 343
• Betamethasone cream (0.1%) 60 g; apply after meals and at bedtime
• Fluocinonide gel/cream 0.05% 60 g; apply after meals and at bedtime
Therapeutics 343
• Betamethasone cream (0.1%) 60 g; apply after meals and at bedtime
• Fluocinonide gel/cream 0.05% 60 g; apply after meals and at bedtime
• Tacrolimus (Protopic) ointment 0.1% 30 g; apply after meals 3 times dailyand at bedtime, do not eat or drink for 30 min; taper frequency depending on response
• Intralesional therapy: triamcinolone acetonide 5–10 mg/mL; inject 1–3 mL per session with sessions at 3–4 wk intervals
• Systemic therapy • Prednisone 5 mg tablets #80
– Take each morning with breakfast for 16 d as 8/d × 4 d, 6/d × 4 d, 4/d × 4 d, 2/d × 4 d, stop
– Will reduce disease activity as topical corticosteroids or systemic NSAIDs are started
• Dapsone 25 mg tablets – Check baseline CBC, liver function tests, urinalysis, and
glucose-6-phosphate dehydrogenase enzyme level before treatment.
– Take each morning with breakfast, 1 × 3 d, 2 × 3 d, 3 × 3 d, 4 × 7 d, and 5 × daily thereafter
– Check CBC and liver function every month for 3 mos, then every 3 mo thereafter.
– Use for long-term control of disease. • Hydroxychloroquine (Plaquenil) 250 mg #100; 2 tablets
with breakfast for 4 wk, then 1 tablet daily for maintenance – Baseline ophthalmology consultation; repeat every 6 mo
to monitor for retinal toxicity