Etiology • Local ischemic injury of salivary gland lobules • May be preceded by trauma or local anesthetic injury, or it
may appear spontaneously
Clinical Presentation • Both major and minor salivary glands can be affected. • Hard palate most common site, usually unilateral • Initially a painful to dysesthetic submucosal swelling • Ultimately, a central necrotic crater develops. • May extend to and involve deep soft tissue and palatal bone
Microscopic Findings • Salivary gland inflammation and lobular necrosis (necrosis is
not always demonstrable on biopsy) • Ductal squamous metaplasia (bland cytology) • Lobular architecture of salivary glands persists
may appear spontaneously
Clinical Presentation • Both major and minor salivary glands can be affected. • Hard palate most common site, usually unilateral • Initially a painful to dysesthetic submucosal swelling • Ultimately, a central necrotic crater develops. • May extend to and involve deep soft tissue and palatal bone
Microscopic Findings • Salivary gland inflammation and lobular necrosis (necrosis is
not always demonstrable on biopsy) • Ductal squamous metaplasia (bland cytology) • Lobular architecture of salivary glands persists
Diagnosis • Microscopic findings
Differential Diagnosis • Salivary gland neoplasm • Squamous cell carcinoma • Granulomatous disease
Treatment • Follow-up only
Prognosis • Excellent