Etiology • Idiopathic or iatrogenic neutropenia • Usually noted when neutrophil count falls below 1,500/mm
Clinical Presentation • Sharply defined ulcer(s), often with minimal peripheral erythema • Ulcer base covered by fibrinous exudate • Wide variation in size of ulcers
Diagnosis • Clinical appearance correlated with results of peripheral blood
count
Clinical Presentation • Sharply defined ulcer(s), often with minimal peripheral erythema • Ulcer base covered by fibrinous exudate • Wide variation in size of ulcers
Diagnosis • Clinical appearance correlated with results of peripheral blood
count
Differential Diagnosis • Major aphthous ulcer • Traumatic ulcer • Necrotizing sialometaplasia • Squamous cell carcinoma
Treatment • Identification and management of underlying neutropenia • Supportive therapy
Prognosis • Relative to ability to manage underlying neutropenia