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Odontogenic Myxoma

Odontogenic Myxoma
Etiology • A benign odontogenic tumor • Unknown origin
Clinical Presentation • A lesion of adulthood (average occurrence at 30 years) • Equal male:female and mandible:maxilla occurrences • Wide age range: second through sixth decades • Usually asymptomatic • May produce jaw expansion
Radiographic Findings • Well-defined, unilocular to multilocular radiolucency • Loculi range from small “honeycomb” to large “soap bubble”

shapes • Cortical thinning may be present with larger lesions. • Perforation of the cortex is uncommon.
Microscopic Findings • Minimal cellularity, myxoid background • Variable amounts of collagen • Scattered residual bony trabeculae • Odontogenic epithelial rests are rarely noted.
Diagnosis • Radiographic features • Microscopic findings
Differential Diagnosis • Other odontogenic tumor: ameloblastoma • Odontogenic cysts: odontogenic keratocyst, dentigerous cyst,
glandular odontogenic cyst • Central giant cell granuloma
Treatment • Excision with bony curettage • Large lesions may require en bloc resection.
Prognosis • Good • Can be aggressive rarely • Recurrences not uncommon, secondary to gelatinous quality
and lack of capsule