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Odontogenic Tumors

Odontogenic Tumors
Adenomatoid Odontogenic Tumor
Etiology • Derivation from epithelial component of the enamel organ • Represents less than 10% of odontogenic tumors • Biologic behavior allows for distinction from ameloblastoma
Clinical Presentation • Narrow age range, 5 to 30 years, with most cases noted during
second decade • Female predilection • Anterior jaw location common • Association with unerupted tooth • Asymptomatic; occasionally produces expansion of alveolar
bone • Rarely occurs in gingival soft tissue (peripheral) • May produce root divergence of adjacent teeth
Radiographic Findings • Well defined, unilocular, often adjacent to crown of unerupted

tooth • Opaque foci may be scattered within the lucency in a
“snowflake” or “salt and pepper” pattern.
Microscopic Findings • Characteristic intraluminal/intracystic growth with well-
defined capsule • Dual cell population: spindle cells and cuboidal to columnar
cells forming tubules or pseudoducts • Foci of dystrophic calcification or eosinophilic droplets may
be noted.
Diagnosis • Radiographic features • Microscopic findings
Differential Diagnosis • Dentigerous cyst • Odontogenic keratocyst • Calcifying odontogenic cyst • Lateral root cyst • Calcifying epithelial odontogenic tumor
Treatment • Enucleation
Prognosis • No recurrence