Etiology • Ameloblastic fibroma: a benign mixed odontogenic tumor withconcomitant epithelial and mesenchymal neoplastic proliferation • Ameloblastic fibro-odontoma: as for ameloblastic fibroma with
the addition of an odontoma • Spontaneous; no known cause for either
Clinical Presentation • Noted mostly in first and second decades • Approximately 70% in mandible, usually posterior region • No gender predilection • May cause jaw expansion • Asymptomatic
Radiographic Findings • Well defined with hyperostotic margin • Unilocular to multilocular • Often associated with an unerupted tooth • Ameloblastic fibro-odontoma has opaque component(s) related
to enamel and dentin in the odontoma component
Diagnosis • Lobulated, cellular mesenchymal component with proliferating
odontogenic epithelium in cords and islands • Enamel matrix, dentin formation associated with odontoma
(when present)
Differential Diagnosis • Ameloblastoma • Dentigerous cyst • Odontogenic keratocyst • Odontogenic myxoma • Central giant cell granuloma
Treatment • Conservative surgical excision/curettage
Prognosis • Excellent
Prognosis • Excellent