Etiology • Most often by members of coxsackievirus group A (7, 9, 10,
and 16) or group B (1–5) • Occasionally due to echovirus 9 or 17
Clinical Presentation • Incubation period of 5 to 9 days • Acute onset • Usually endemic in young children; usually occurs in summer • Often subclinical • Posterior oral cavity, tonsillar pillars involved • Macular erythematous areas precede short-lived vesicular erup-
tion, followed by superficial ulceration • Accompanied by pharyngitis, dysphagia, fever, malaise,
headache, lymphadenitis, and vomiting • Self-limiting course, usually under 2 weeks
Diagnosis • Other viral illnesses to be ruled out or separated • Course, time of year, location of lesions, contact with known
infected individual
Differential Diagnosis • Hand-foot-and-mouth disease • Varicella • Acute herpetic gingivostomatitis
Treatment • Soft diet • Hydration • Antipyretics • Chlorhexidine rinses • Compounded mouth rinses
Prognosis • Excellent
and 16) or group B (1–5) • Occasionally due to echovirus 9 or 17
Clinical Presentation • Incubation period of 5 to 9 days • Acute onset • Usually endemic in young children; usually occurs in summer • Often subclinical • Posterior oral cavity, tonsillar pillars involved • Macular erythematous areas precede short-lived vesicular erup-
tion, followed by superficial ulceration • Accompanied by pharyngitis, dysphagia, fever, malaise,
headache, lymphadenitis, and vomiting • Self-limiting course, usually under 2 weeks
Diagnosis • Other viral illnesses to be ruled out or separated • Course, time of year, location of lesions, contact with known
infected individual
Differential Diagnosis • Hand-foot-and-mouth disease • Varicella • Acute herpetic gingivostomatitis
Treatment • Soft diet • Hydration • Antipyretics • Chlorhexidine rinses • Compounded mouth rinses
Prognosis • Excellent