• Topical therapy
• Penciclovir cream (Denavir) 1% 1.5 g tube; apply at the onset of symptoms every 2 h × 4 d
• Docosanol cream (Abreva) 10%; apply topically at the onset of symptoms q2–3h 5 times daily
• Acyclovir ointment 5% 3 g tube; apply at the onset of symptoms 6 times daily × 7 d
• Penciclovir cream (Denavir) 1% 1.5 g tube; apply at the onset of symptoms every 2 h × 4 d
• Docosanol cream (Abreva) 10%; apply topically at the onset of symptoms q2–3h 5 times daily
• Acyclovir ointment 5% 3 g tube; apply at the onset of symptoms 6 times daily × 7 d
• Systemic therapy • Acyclovir 200 mg tablets #35
– 1 tablet 5 times daily × 7 d – Start medication with premonitory symptoms to shorten
the course of the episode. • Acyclovir 200 mg tablets
– 3 tablets daily to prevent reactivation in bone marrow transplant recipients
Sjögren’s Syndrome • Topical therapy
• Moisten mouth with cool water or ice chips. • Avoid alcohol-containing mouth rinses. • Avoid drugs that produce xerostomia. • Limit caffeine intake. • Use Vaseline on lips at night (a thin coating). • Drink milk with meals
• Saliva substitutes • Liquid, tablet, or gel forms • Available over the counter
• Systemic therapy • Pilocarpine (Salagen) 5 mg tablets #100; take 1 tablet
3 times daily • Cevimeline capsules (Evoxac) 30 mg capsules #100; take
1 capsule 3 times daily